López, the son of Bartolomé López and María de la Trindad, was admitted to the choir of Mexico City Cathedral around 1625. He attended the University of Mexico and graduated in theology. He was the assistant organist of Juan Gutiérrez de Padilla. Within four days of Ximeno's death, López was appointed organist as well maestro de capilla. It was from then on that he changed his name to López Capillas (López of the Chapels).
At the time of his death, it was noted that López was earning 1000 pesos. That was one of the largest salaries received by a Mexican church musician during the time. His works were all written according to the prima practica.